Compounding: Ageless Art
Meets Technology
The retail pharmacy industry has always been primarily a story of very dedicated people serving by providing medications and related items to their fellow man and by lending a sympathetic ear to their concerns. Pharmacists have consistently been near the top of the list of "Most Trusted Professionals."
Before the advent of large-scale pharmaceutical manufacturing, beginning in the 1950s, the neighborhood pharmacist mostly filled doctor’s orders by personally preparing (or compounding) each medication from bulk chemicals and other ingredients, customizing each order to the individual.
"In other words, the pharmacist of the early 20th century made everything from scratch!" said pharmacist Bruce Hinshaw, owner of Cardinal Pharmacy in New Castle. "Many advances were made with the onset of large scale drug manufacturing by pharmaceutical companies. More medication treatment options are available now than ever before. The role of the pharmacist has changed from that of a ‘chemist’ to that of a distributor of manufactured drug products and a provider of information concerning their use."
But all progress comes with a price. The pharmaceutical manufacturing process has standardized the drug product available, which allows for the application of drug treatment to a wide spectrum of individuals. However, persons with unique needs, needs not met by mass produced products, have until recently been denied full benefit of specialized or customized drug therapy. In the past 10 to 15 years in America, the art and science of pharmacy compounding has enjoyed a revival. Many pharmacists have undergone specialized training, purchased special equipment and built laboratories in which to prepare custom preparations for special human and animal populations.
Here are a few of the many examples of how customized medication compounding can help people:
® Placing an anti-inflammatory drug in a specially designed gel to allow for the delivery of medication directly to an arthritic knee thus avoiding causing stomach and intestinal damage to a patient already suffering from stomach or intestinal disease. It could also help avoid widespread distribution of the drug in an elderly person with compromised liver function.
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Providing a medication in a commercially unavailable dosage form to allow for better delivery to a particular patient. For instance, making a liquid suspension of a heart medicine to an infant or a person with swallowing difficulties, or placing hemorrhoid medications in a uniquely designed "rectal rocket" to provide faster relief.Providing medication free of dye, lactose, of other additives that a particular person may be allergic to.
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Using bio-identical (as opposed to synthetic) hormones in creams, gels, capsules, suppositories, and troches for helping solve problems of menopause, PMS, andropause, decreased sex drive, and other hormonally related issues.®
Mixing multiple agents in one product to diminish the cost or increase the compliance of therapy. An example would be placing three to four medications in a gel to treat diabetic neuropathy or using several drug agents to help heal a difficult-to-treat bed sore.Pharmacists have built state-of-the-art prescription compounding laboratories that allow for the best environment in which to prepare medications for their clients. They follow specific procedures to insure consistency, sterility, potency, and elegance of product made.
At Cardinal Pharmacy’s compounding practice, they specialize in pain management, veterinary compounding, respiratory formulas and bio-identical hormone replacement therapy. Other areas of practice include wound management, ophthalmic, pediatrics and nutrition, among many others.
It takes a special synergy to make compounding successful, he said.
"It is necessary to have a dedicated and specially trained pharmacist, a compliant patient, and a caring and resourceful physician to achieve success," he explained. "Compounding pharmacists typically get involved on a much more personal level with their patients and achieve remarkable outcomes.
By going back to their professional roots, compounding pharmacists have opened whole new avenues of drug treatment for individuals or physicians who need help beyond manufactured pharmaceuticals. These pharmacists have added innovative practice methods with the trust that the public places in them to deliver a whole new level of care to people seeking help.